Abstract
The visible light reactions of noble metal-based photocatalysts have been increasingly utilized to investigate their antibacterial activities. Furthermore, the photoreactions at various visible light wavelengths for specific combinations of titania nanotubes and noble metal nanoparticles have been found to promote osteogenic functionality. In this investigation, a novel multi-coating combination of noble metals (gold and platinum) on titania nanotubes was assessed using plasmonic photocatalysis and low-level laser therapy at 470 and 600 nm. The results showed that this coating on the nanotubes promoted antibacterial activity and osteogenic functionality. The order in which the gold and platinum coatings were layered onto the titania nanotubes strongly affected the osteogenic performance of the human mesenchymal stem cells. These results have identified a new approach for the development of efficient novel combinations of noble metal nanoparticles and titania nanotubes with visible light responses, sustainable antimicrobial activity, and osteogenic functionality.
Highlights
Ideal implant success in dentistry occurs when there is stable functionality of the dental prosthesis, which results from a strong bonding force based on high-quality osseointegration without infection in the region of the peri-implant soft tissue
The field-emission scanning electron microscope (FE-SEM) images confirmed that the agglomeration and coarsening of the sputtered nanoparticles were formed at the surface of the TiO2 nanotubes coated with Au and Pt for
To better understand the correlation between the wavelength of visible light and osteogenic differentiation, we investigated the morphologies of the human mesenchymal stem cells (hMSCs) cultured on the surface of the experimental specimens by FE-SEM
Summary
Ideal implant success in dentistry occurs when there is stable functionality of the dental prosthesis, which results from a strong bonding force based on high-quality osseointegration without infection in the region of the peri-implant soft tissue. Implant failure can be classified as early, which occurs during the initial loading period, or delayed, which occurs after the osseointegration process has been completed and implant function is achieved. To improve the limitations of conventional antibacterial treatment methods such as a direct injection of antibacterial drugs, new technologies such as antimicrobial biomolecules [4,5,6], antibacterial nanoparticles [7,8,9], photodynamic therapy [10,11,12], and photocatalytic therapy [13,14,15] have been introduced. Titania (TiO2 ) based photocatalytic antibacterial treatments are predicted to be useful for dental and medical implants based on titania or titania alloys
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