Abstract

Heterotopic or ectopic mucosa is ongenital anomaly elucidated as the inhabitance of tissue outside its habitual locale. This tissue is discerned coincidentally and may be asymptomatic or with nonspecific gastrointestinal symptoms. Two categories of heterotopic tissue predominantly crop up in the gastrointestinal tract, PANCREATIC and GASTRIC. Isolated heterotopic gastric mucosa (HGM) can arise at all position’s, anywhere along the gastrointestinal tract, from the oesophagus to the rectum. The incidence is sporadic but should be deliberated upon in the differential diagnosis of unexplained pain of the abdomen, bleeding from the gastrointestinal tract or weight loss. Once heterotopia is identified, suitable treatment can be instituted thereby diminishing the danger of complications. Heterotopic or Ectopic tissue is a congenital anomaly, attributed to abnormal embryologic development, of the existence of tissue apart from the typical location, with no neural, vascular, anatomic relation with the main body of an organ in which it customarily exists. Heterotopic gastric mucosa (HGM) was initially detailed by Ewell and Jackson in 1939. The congenital anomaly can be emulated by acquired transition (e.g. pyloric epithelial lining) in some organs e.g. lower oesophagus, duodenal bulb and gall bladder. HGM can appear at any location in the gastrointestinal tract, however, it is exceptional in the lower alimentary canal.

Highlights

  • The complete oesophagus is afflicted by heterotopic gastric mucosa (HGM) as an inlet or cervical inlet area in the proximal oesophagus (HGMPE)

  • Epithelium simulating gastric mucosa of the nonspecialized antral or pyloric type is perceived in inflammatory bowel disease, duodenitis, peptic ulcer etc. and is a scrupulous metaplastic distortion, contingent to chronic inflammation

  • HGM is correlated with concurrent fundic gland polyps and duodenitis

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Summary

Introduction

The complete oesophagus is afflicted by HGM as an inlet or cervical inlet area in the proximal oesophagus (HGMPE). It is a congenital anomaly which prevails in up to 10% of the population. Autopsy exhibits up to 70% extent of HGM in the normal population. A flat, salmon coloured patch is located in the proximal 1/3rd of the oesophagus, distal to upper oesophageal sphincter [1]. The recognition is circumstantial, happening during retraction of the endoscope, done for appraisal of gastrointestinal complaints. Epithelium simulating gastric mucosa of the nonspecialized antral or pyloric type is perceived in inflammatory bowel disease, duodenitis, peptic ulcer etc. Elaborate application of fibre optic endoscopy from upper gastrointestinal tract allows the elucidation of HGM (Table 1)

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