Abstract
Establishing what fraction of immobilised cells is biocatalytically active, and deciding how the reaction rates in an immobilised cell aggregate should be described, are important problems in the design and modelling of immobilised cell systems. In this paper the specific ATP concentration (SATP) and the specific oxygen uptake rates (SOUR) in freely suspended and immobilised cells of Beneckea natriegens growing on support particles in a three phase air lift reactor are compared, and found to be markedly different. It is demonstrated that the composition (quality) of the biomass and its catalytic activity vary with specific growth rate in the freely suspended culture, and a compartmental model of cell growth is used to correlate this freely suspended cell data. This compartmental model is then applied to the description of the immobilised cell system at steady state, and used to explain the observed variations in SATP and SOUR.
Published Version
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