Abstract
Viability of human dermal fibroblasts cultured on bacterial cellulose and Aloe vera composites
Highlights
Development of multifunctional scaffolds has allowed restructuration and improvement of native tissues, presenting characteristics that mimic complex tissues formation [1]
Groups of investigation consisted of pure bacterial cellulose (BC) and BC composed with fractions of Aloe vera extract Cell viability was determined using the colorimetric assay MTS [3-(4,5- dimethylthiazol2-yl)-5-(3-carboxymethoxyphenyl) 2-(4-sulfophenyl)-2Htetrazolium]
Results indicated a good interaction between the cells and the BC composites, which was indicated by the stable cell viability observed over time
Summary
Development of multifunctional scaffolds has allowed restructuration and improvement of native tissues, presenting characteristics that mimic complex tissues formation [1]. Biocompatibility, mechanical properties and water retention are other important characteristics of biomaterials used for tissue regeneration [2]. In this perspective, searching for a biomaterial that promote healing and cell development, fractions of Aloe vera combined with bacterial cellulose (BC) are being intensively studied in our laboratory. The combination of biological components of a natural plant and the unique properties of BC is believed to promote desirable hydrogel-cell interactions and improvement of the healing dynamics of injured tissues [5]. The objective of this study was to evaluate the viability of human dermal cells when in contact with the novel BC-Aloe vera composites
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