Very rapid synthesis of highly efficient and biocompatible Ag2Se QD phytocatalysts using ultrasonic irradiation for aqueous/sustainable reduction of toxic nitroarenes to anilines with excellent yield/selectivity at room temperature

Abstract

There are many problems associated with the synthesis of nanocatalysts and catalytic reduction of nitroarenes - e.g., high temperatures, costs, long reaction/synthesis process times, the toxicity of chemicals/solvents, undesirable byproducts, the toxic/harmful wastes, low efficiency/selectivity, etc. This study represents an attempt to overcome these challenges. To this purpose, biocompatible and highly efficient Ag2Se quantum dots (QDs) catalysts with antibacterial activity were synthesized in a very rapid (30 sec, rt), simple, inexpensive, sustainable/green, and one-pot strategy in water using ultrasonic irradiation. Characterization of the QDs was performed using different techniques. UV–Vis absorption and fluorescence spectroscopic studies showed an absorption peak at 480–550 nm and a maximum emission peak around 675 nm, which confirmed the successful synthesis of Ag2Se QDs via the applied biosynthetic method. Subsequently, catalytic reduction of nitroarenes by them was carried out under safe conditions (H2O, rt, air atmosphere) in ∼ 60 min with excellent yield and selectivity (>99%). Their catalytic activity in the reduction of various toxic nitroarenes to aminoarenes under green conditions was investigated. Thus, a rapid and safe ultrasound-based method was employed to prepare stable and green Ag2Se QDs phyto-catalysts with unique properties, including exquisite monodispersity in shape (orthorhombic) and size (∼7 nm), air-stability, and good purity and crystallinity. Importantly, instead of various toxic chemicals, the plant extract obtained by rapid ultrasonic method (10 min, rt) was used as natural reducing, capping, and stabilizing agents. Moreover, antibacterial assays results showed that Ag2Se-QDs catalysts at low concentrations (ppm) have high activity against all tested bacteria, especially E. coli (MIC:31.25 ppm, MBC:125 ppm) which were significantly different from those of Fig extract (MIC = MBC:500 ppm). The data reflect the role of these bio-synthesized Ag2Se-QDs catalysts in the development of versatile and very safe catalysts with biomedical properties.