Verniks Kazeoza Maddesinde Bulunan Bazı Element (Na+, Cl-, K+, Fe+2, Mg+2, Ca+2, Cu+2, Zn+2) Düzeylerinin Değerlendirilmesi

Abstract

The substance "Vernix Caseosa" (VC), which begins to be secreted in the third trimester of the human fetus, is a natural product that occurs spontaneously. This substance, which protects the baby against external factors, has a feature that facilitates birth by providing lubrication during normal birth. 52 infants were included in the study. A sterile soft-tipped device was used to collect the VC, and a swab was taken from the baby's skin immediately after birth. In addition, mothers under the age of 35 and over the age of 35 were grouped as multiparous and nulliparous and their VC was examined separately. In VC, the levels of the elements responsible for production and repair in the human body were investigated. Homogenized samples were measured by Atomic Absorption Spectrophotometer. Element results were given as mean and standard deviation; *Na+: 12.09 ± 0.58, *Cl-: 10.27 ± 1.08, *K+:1.84 ± 0.54, **Fe+2: 72.39 ± 4.84, **Mg+2: 67.07 ± 3.31, **Ca+2:864.51 ± 32.61, **Cu+2:12.98 ± 2.01, **Zn+2: 11.00 ± 1.55 (*:mg/g tissue, **:ug/g tissue). According to the results of literature review and to the best of knowledge, limited information on element levels of VC has been reported. The studied elements are found as cofactors in growth and development and in many biochemical mechanisms. Protein and lipid contents have been investigated in previous studies and it has been reported that VC has an important role in protecting the fetus from external factors and infections. In addition, the protection of amniotic fluid from maceration and the prevention of fluid and electrolyte losses of the skin are also mentioned. It is thought that this research will make an important contribution to the determination of the biochemical structure of VC, which is a natural and protective substance.