Abstract
A preparation (Vasolastine 3) containing a rather formidable number of lipotropic enzymes, as well as two proteolytic enzymes active in the metabolism of amines, was evaluated clinically following an earlier animal study. These enzymes are obtained from Crucifer seeds and contain the following systems: fatty acid activator, co-enzyme A, acyl dehydrogenase, cleavage and condensing enzymes, adenosine triphosphate, dephosphopyridine nucleotide, and cholesterol esterase; in addition, amino acid-oxidase and tyrosinasetryptase were included. This study was initiated following encouraging therapeutic reports in the literature. Twelve patients were included in this series; 6 were diagnosed chronic brain syndrome associated with cerebral arteriosclerosis, the other 6 were classified as chronic brain syndrome associated with senile and presenile brain disease with circulatory disorders. The patients were transferred either from an admission ward or from a state hospital to a research ward. Personnel were available to provide special occupational and recreational therapy for a geriatric group. The nursing care was sufficient to train and encourage the patients to fit into an active ward routine. The preparation was given intramuscularly over a period of 30 to 90 days in a dosage of 2 cc. three to seven times a week.
Published Version
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