Abstract
Angiological screening was performed to determine the cardio-ankle vascular index (CAVI) in 224 young people to determine their vascular aging phenotype. All subjects were divided into CAVI-tercile groups. According to the experts views the upper tercile of this distribution corresponds to early vascular aging or EVA syndrome. Lower tercile corresponds to favorable one and average tercile – to normal vascular aging. In these CAVI-tercile groups, the representation of individuals with signs of arterial hypertension/prehypertension (AH/PH) and overweight was evaluated. It turned out that among boys and girls with risk factors (RF), carriers of various vascular phenotypes are noted, from favorable one to early vascular aging. Such data indicate the need to form youth risk groups, taking into account the presence of not only classical RF, but also the assessment of vascular stiffness. The obtained data is useful to take into account in the process of youth medical examination in order to further develop more individualized preventive intervention programs for each young person.
Highlights
Worldwide, cardiovascular (CV) mortality remains at a high level [1], due to a wide spread of risk factors (RF), including premature vascular aging, determined by the level of arterial wall stiffness, which is regarded as implemented RF [2]
It is necessary to establish a system of wide angiological screening among young people as soon as possible, since this group has the maximum chance of inhibiting vascular remodeling in the case of preventive intervention [4]
According to the data of the tercile analysis, carriers of EVA-syndrome were characterized by the presence of cardio-ankle vascular index (CAVI) from 6.1 to 8.1, and carriers of favorable vascular aging differed in CAVI from 3.2 to 5.6
Summary
Cardiovascular (CV) mortality remains at a high level [1], due to a wide spread of risk factors (RF), including premature vascular aging, determined by the level of arterial wall stiffness, which is regarded as implemented RF [2]. From a biological point of view, it is the vessels that begin to age earlier than other organs and tissues For this reason, it is necessary to establish a system of wide angiological screening among young people as soon as possible, since this group has the maximum chance of inhibiting vascular remodeling in the case of preventive intervention [4]. The features of such associations are clearly insufficiently studied, as well as the possibility of using the vascular age indicator to motivate young people to conduct preventive interventions and monitor their effectiveness
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
