Abstract
Vasculitis is a group of clinicopathological entities involving inflammation of the blood vessel walls. The different forms of vasculitis may vary in terms of aetiology, pathogenesis, type, and calibre of vessel involved, type of inflammation, preferential organ distribution, clinical manifestations, genetic predisposition, and demographic characteristics. The classification most widely used currently is based on the nominal definitions proposed by the International Chapel Hill Consensus Conference (CHCC) in its 2012 revision. The aetiology of vasculitis is still not fully understood, despite recent advances in the study of genetics and pathogenesis. Due to the variability of vasculitis, there is no single, uniform diagnostic method. Diagnosis of vasculitis is challenging in most cases. However, a detailed clinical history, careful physical examination and appropriate laboratory tests from the information obtained from them are necessary in all types of vasculitis to establish a correct diagnosis, its probable date and manner of onset, the organs or systems affected and the extent of disease.
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