Vascular Precursors: Origin, Regulation and Function

Abstract

Series Editor: Karen K. Hirschi ATVB In Focus Vascular Precursors: Origin, Regulation and Function Articles in this series: •Hirschi KK. Vascular Precursors: Origin, Regulation and Function. Arterioscler Thromb Vasc Biol . 2010;30:1078–1079. •Kumar AHS, Caplice NM. Clinical potential of adult vascular progenitor cells. Arterioscler Thromb Vasc Biol . 2010;30:1080–1087. •Dimmeler S. Regulation of bone marrow-derived vascular progenitor cell mobilization and maintenance. Arterioscler Thromb Vasc Biol . 2010;30:1088–1093. •Yoder MC. Is endothelium the origin of endothelial progenitor cells? Arterioscler Thromb Vasc Biol . 2010;30:1094–1103. •Corselli M, Chen C-W, Crisan M, Lazzari L, Peault B. Perivascular ancestors of adult multipotent stem cells. Arterioscler Thromb Vasc Biol . 2010;30:1104–1109. •Iacobas I, Vats A, Hirschi KK. Vascular potential of human pluripotent stem cells. Arterioscler Thromb Vasc Biol . 2010;30:1110–1117. In this miniseries, we discuss the phenotype, origin, and specialized microenvironment (niche) of distinct populations of stem and progenitor cells that exhibit vascular potential. Their usefulness and effectiveness for clinical therapies are also described. We have learned a great deal about postnatal vascular …