Vascular mimicry in head and neck tumours

Tahwinder Upile,Colin Hopper,Jaspal Mahil,Waseem Jerjes

doi:10.1186/1758-3284-1-s1-p15

Tahwinder Upile, Colin Hopper + Show 2 more

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https://doi.org/10.1186/1758-3284-1-s1-p15

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Abstract

Introduction Angiogenesis has been extensively investigated in several tumour models; however, chemotherapeutic agents based upon these models have not been very effective. It is logical to assume this lack of efficacy is due to the host tumour interface. Furthermore, it is a reasonable hypothesis that the transition between the host vasculature and tumour is not binomial but a gradual transition from tumour and mosaic vessels to host capillaries. The existence of such pure tumour and mosaic vessels would suggest the possibility of tumour vascular mimicry in the connecting vessels.

Highlights

Angiogenesis has been extensively investigated in several tumour models; chemotherapeutic agents based upon these models have not been very effective
1S1.pdcientific Meeting of the Head and Neck Optical Diagnostics Society Colin Hopper, Adel K El-Naggar, Tahwinder Upile, Waseem Jerjes and HJCM Sterenborg Publication of this supplement was made possible with support from KARL STORZ Endoskope Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/pdf/
The existence of such pure tumour and mosaic vessels would suggest the possibility of tumour vascular mimicry in the connecting vessels

Summary

Vascular mimicry in head and neck tumours

Address: Head & Neck Centre, University College London Hospitals, London, UK * Corresponding author from 1st Scientific Meeting of the Head and Neck Optical Diagnostics Society London, UK. 14 March 2009. Address: Head & Neck Centre, University College London Hospitals, London, UK * Corresponding author from 1st Scientific Meeting of the Head and Neck Optical Diagnostics Society London, UK. Published: 28 July 2009 Head & Neck Oncology 2009, 1(Suppl 1):P15 doi:10.1186/1758-3284-1-S1-P15. 1S1.pdcientific Meeting of the Head and Neck Optical Diagnostics Society Colin Hopper, Adel K El-Naggar, Tahwinder Upile, Waseem Jerjes and HJCM Sterenborg Publication of this supplement was made possible with support from KARL STORZ Endoskope Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/pdf/

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