Abstract
Angioleiomyoma is a benign neoplasm with perivascular smooth muscle origin and is rare in the mouth. A male patient presented to our service with the chief complaint of an asymptomatic facial lesion. In the intraoral examination, a 1.5-cm submucosal nodule in the left cheek was observed. Doppler ultrasonography showed an image of a lobulated, hyperechoic nodule with defined limits and no change in the blood flow. The clinical hypotheses were lipoma, solitary fibrous tumor, and salivary gland neoplasm. Histologic examination after excisional biopsy revealed a delimited lesion, presenting multiple vascular spaces of varying sizes and calibers, sometimes congested and interconnected, covered by endothelium and spindle cell layers of variable thickness. A mixed thrombus with an organization area composed of granulation tissue was also found. Neoplastic cells were immunoreactive for smooth muscle actin and negative for CD34, confirming the diagnosis of angioleiomyoma. After 6 months of follow-up, no signs of recurrence were observed.
Published Version
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