Variation in Total Phenolic and In-vitro Antioxidant Activities of Mentha longifolia L. From Azad Jammu and Kashmir Territory

Abstract

The examination was done to decide the all-out phenolics, all-out flavonoids, and in-vitro antioxidants of M. longifolia gathered from various areas (Rawalakot, Khaigala, Akhorban, Alisojal, Phirkot, Bhaikh, and Singola) of Poonch, Azad Jammu, and Kashmir. The watery concentrates of M. longifolia were surveyed for absolute phenolics, all-out flavonoids, restraint against thiobarbituric acid reactive species (TBARS) prompt by various star oxidants (10µM FeSo4 and 5µM sodium nitroprusside) in mice liver and brain homogenates, DPPH radical searching limit, iron-chelating power. The outcomes demonstrated that M. longifolia contained a generous level of phenolic (192.10±2.10 mg/g) and flavonoid compounds (4.23±0.03 mg/g) separately. Among various areas, the Alisojal indicated the most elevated antioxidant movement against lipid peroxidation prompted by iron in mice liver (IC50, 23.67±2.67 µg/ml) and brain (IC50, 13.85±0.85 µg/ml) and showed the most noteworthy cell reinforcement action against sodium nitroprusside in mice liver (IC50, 14.76±1.76 µg/ml) and brain (IC50, 14.05±1.05 µg/ml). The concentrates of various areas likewise demonstrated promising DPPH radical searching (IC50, 30.47±1.47 - 71.77±2.77 µg/ml) and metal-chelating activities (IC50, 40.67±0.89 - 90.92±3.92 µg/ml). In general, it was presumed that M. longifolia may be an expected wellspring of phenolic and flavonoid mixes bearing a considerate of the antioxidant character towards animal tissues.