Variation in the Composition Properties and its Effect on the Mechanical Properties of a cortical bone

Abstract

Cortical bone is a composite material with varying mechanical properties as per the anatomical locations, orientations, etc. The relationship between bone cortical composition properties and compressive mechanical strength is important for selecting the right scaffold material. The findings show that the mineral content consisting mainly of hydroxyapatite crystals has a positive effect on the mechanical properties of the cortical bone, that is, an increase in the mineral content can increase the load capacity of the scaffold. According to this study, wet and dry densities equally impact the compressive strength and modulus of cortical bone. In addition, the presence of water degrades the quality of bone and reduces its ability to function, the variation in composition and its effect on mechanical properties must be considered when creating Scaffolds. The findings highlight the need to consider the properties of these composites when selecting scaffold materials for tissue engineering. The results of this study may help create biomimetic scaffolds with enhanced properties that support tissue regeneration and integration.