Abstract
Objectives: While many guidelines recommend treatment to specific LDL-C targets, the 2013 ACC/AHA guidelines recommend specific doses of individual statins according to the patient's cardiovascular risk. Using the specific dose approach, it is unclear what proportion of patients will need modification of treatment due to inadequate lowering of LDL-C. This study aimed to use individual patient data from the VOYAGER meta-analysis to describe the variability in LDL-C reduction following treatment with different statins and doses.
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