Abstract
Objective To investigate the diagnostic value of delayed water enema 18F-FDG PET/ CT for rectal cancer.Methods Sixty-nine cases (52 males,17 females; average age 57.9 years) with clinically suspected rectal cancer underwent routine and delayed water enema 18F-FDG PET/CT.The imaging results were compared with colonoscopy and surgical pathology.The diagnostic efficiency of the two imaging methods was compared and so was the SUVmax of lesions.Paired t and McNemar test were used to analyze the data.Results There were 61 rectal cancer cases confirmed by pathology.The SUVmax of rectal cancer calculated from routine and delayed water enema 18F-FDG PET/CT was significantly different (13.17± 6.19 vs 14.25±6.63; t=-6.100,P＜0.01).The sensitivity,specificity and accuracy of routine 18F-FDG PET/CT and delayed water enema 18F-FDG PET/CT in diagnosis rectal cancer were 90.2％ (55/61) vs 98.4％(60/61),4/8 vs 6/8,85.6％(59/69) vs 95.7％(66/69).A statistically significant difference was found in diagnostic accuracy between the two imaging methods (x2=5.140,P＜0.05).Conclusion The delayed water enema 18F-FDG PET/CT has a complementary diagnostic value for routine 18F-FDG PET/CT in rectal cancer. Key words: Rectal neoplasms; Enema; Tomography, emission-computed; Tomography, X-ray computed; Deoxyglucose
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