Abstract
To analyse the diagnostic accuracy of computed tomography (CT) in ventilator-associated pneumonia (VAP). 23 patients on mechanical ventilation with a new pulmonary abnormality on chest X-ray were examined with both spiral-CT and high-resolution CT. The diagnosis VAP was made according to prospectively defined criteria. Bronchoscopic specimen asservation with protected specimen brushing (PSB) served as gold standard. With PSB, 11 of 23 patients were found to have VAP. CT showed a sensitivity and specificity of 53% and 63%, respectively. Ground glass infiltrates appeared to have a 100% specificity but were found in only 5/11 patients. CT is not the method of choice for diagnosing VAP. Ground glass infiltrates seeming to be highly specific are only inconstantly found.
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