Abstract
Diagnosis of Ventilator-Associated Pneumonia: Where Do We Go from Here?
Highlights
Clinical criteria have been used by clinicians and researchers to define nosocomial pneumonia
Specimens obtained by protected specimen brush (PSB), Bronchoalveolar lavage (BAL) and Protected BAL (PBAL) are cultured quantitatively as a further step to differentiate colonization and infection and results expressed as the number of colony forming units per millilitre
More recently investigators have compared blindly collected PSB and BAL specimens to those obtained through bronchoscopy in an attempt to find noninvasive diagnostic tests
Summary
Clinical criteria have been used by clinicians and researchers to define nosocomial pneumonia. Fagon et al [11] validated the PSB test in 147 ICU patients, comparing it with clinical definitions for pneumonia or autopsy findings. Based on postmortem findings as the comparator, have they provided more information on the performance characteristics of invasive (and noninvasive) tests, but they have provided insight into the nature of ventilator-associated pneumonia.
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