Abstract
The presence of jaundice in a patient is a distinct concern to the clinician. He is confronted at the outset with its medical or surgical implications. For the differentiation of this jaundice, a number of clinical and laboratory methods are available; of these, the cholesterol ester fraction has been of particular interest to us. In a discussion of the subject, Sidney A. Portis, 1 on the basis of his clinical observations, remarked that in obstructive jaundice the cholesterol esters are often diminished before any other liver function tests give abnormal results. A review of the literature revealed a number of contradictory statements on this matter. The significance of a low cholesterol ester ratio of the serum in cases of parenchymatous jaundice has been well established. 2 It has been generally agreed that the liver cell esterifies cholesterol and that injury to the liver cell or decrease of its function interferes
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