Abstract
Differences in serum lipids, apoprotein levels, and fatty acid compositions were investigated in normal and hyperlipidemic female subjects in a rural area of Japan. Compared with normolipidemic subjects, hyperlipidemic ones of type IIa showed only slight differences in fatty acid composition in the cholesterol ester fraction. Also compared with normolipidemic subjects, the type IIb group had a lower proportion of 18:2 fatty acids in the phospholipid fraction, while 16:1 and 18:1 fatty acids were higher and 18:2 fatty acids were lower in the cholesterol ester fraction. Regarding type IV hyperlipidemics vs. normolipidemics, differences were evident in that in the former percentages of 18:2 fatty acids were lower in the cholesterol ester, phospholipid, and triglyceride fractions, while the percentages of 16:0 fatty acids were higher in the cholesterol ester and triglyceride fractions and that of 22:6 fatty acid in the phospholipid fraction was higher. Dietary fatty acid composition and cholesterol intake did not differ significantly among the groups.
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