Abstract
Liquid Chromatography-Mass Spectrometry (LC-MS) is becoming more and more widely used in clinical laboratory, and LC-MS related quality management requires more rigid than it was. According to CLSI C62-A, this article provides a reference for the validation procedure of LC-MS assay, including limit of detection and lower limit of the measuring interval, linearity and dilution, imprecision, assay interferences and trueness. (Chin J Lab Med, 2016, 39: 991-994) Key words: Chromatography, liquid; Mass spectrometry; Clinical Laboratory technirques
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