Abstract

In the era of precision medicine, liquid chromatography-mass spectrometry (LC-MS) will continue to have significant impact on laboratory medicine in spite of the inherent challenges posed by the technology. It seeks to explain what is clinical mass spectrometry , and describes its basic framework and life cycle. It concludeds the key points of clinical LC-MS through the practical experiences of CLSI guideline and Cleveland health care clinical mass spectrometry laboratory. It then illustrates the challenges of appropriately applying LC-MS to clinical diagnostics through comparisons with research based LC-MS utilizations. Furthermore, It attempts to elucidate the challenges and endeavors It has made toward implementing clinical LC-MS in China. Finally, It discusses the prospective future of LC-MS in clinical diagnostics.(Chin J Lab Med, 2017, 40: 737-734) Key words: Chromatography, liquid; Mass spectrometry; Clinical laboratory techniques

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.