Validation of bioimpedance phase angle in lower extremity of male patients with chronic spinal cord injury.

Abstract

[Purpose] This study aimed to evaluate the relationship between lower extremity phase angle and muscle thickness/echo intensity in males with chronic spinal cord injury. It also compared bioelectrical impedance analysis measurements to investigate skeletal muscle degeneration between individuals with spinal cord injury and healthy controls. [Participants and Methods] This cross-sectional study included 12 male patients with chronic spinal cord injury and 14 healthy male controls. We used bioelectrical impedance analysis and ultrasonography to measure the lower extremity phase angle and muscle thickness/echo intensity of the rectus femoris muscle, respectively. We also compared the bioelectrical impedance analysis measurements between individuals with spinal cord injury and healthy controls. [Results] Lower extremity phase angle was strongly correlated with muscle thickness and echo intensity of the rectus femoris muscle in individuals with spinal cord injury. All measures differed significantly between individuals with spinal cord injury and healthy controls. [Conclusion] These findings suggest that lower extremity phase angle is a valuable skeletal muscle indicator in spinal cord injury. Furthermore, bioelectrical impedance analysis revealed degeneration of the lower extremity skeletal muscles in individuals with chronic spinal cord injury.