Abstract
Comorbid infections have a significant effect on morbidity and mortality in modern rheumatology, especially in immune-mediated inflammatory rheumatic diseases (IMIRD). In this regard, vaccination is becoming increasingly important in the prevention of infections in IMIRD. The article analyzes an updated version of the recommendations for vaccination of adult patients with IMIRD, proposed by experts of the European League Against Rheumatism at the end of 2019. The safety and immunogenicity of vaccination associated with the prevention of various infections in patients with IMIRD are discussed. The main directions of future research on this issue are outlined.
Highlights
 ñîâðåìåííîé ðåâìàòîëîãèè êîìîðáèäíûå èíôåêöèè îêàçûâàþò çíà÷èòåëüíîå âëèÿíèå íà ìîðáèäíîñòü è ëåòàëüíîñòü, îñîáåííî ïðè èììóíîâîñïàëèòåëüíûõ ðåâìàòè÷åñêèõ çàáîëåâàíèÿõ (ÈÂÐÇ)
Comorbid infections have a significant effect on morbidity and mortality in modern rheumatology, especially in immune-mediated inflammatory rheumatic diseases (IMIRD)
Vaccination is becoming increasingly important in the prevention of infections in IMIRD
Summary
 ñîâðåìåííîé ðåâìàòîëîãèè êîìîðáèäíûå èíôåêöèè îêàçûâàþò çíà÷èòåëüíîå âëèÿíèå íà ìîðáèäíîñòü è ëåòàëüíîñòü, îñîáåííî ïðè èììóíîâîñïàëèòåëüíûõ ðåâìàòè÷åñêèõ çàáîëåâàíèÿõ (ÈÂÐÇ). 1. Âàêöèíàöèþ ïðîòèâ ãðèïïà ñëåäóåò íàñòîÿòåëüíî ðåêîìåíäîâàòü áîëüøèíñòâó áîëüíûõ ÈÂÐÇ 2. Âàêöèíàöèþ ïðîòèâ ïíåâìîêîêêîâîé èíôåêöèè ñëåäóåò íàñòîÿòåëüíî ðåêîìåíäîâàòü áîëüøèíñòâó áîëüíûõ ÈÂÐÇ 3. Âàêöèíàöèþ ïðîòèâ ãåïàòèòîâ À è  ñëåäóåò íàçíà÷àòü áîëüíûì ÈÂÐÇ èç ãðóïïû ðèñêà (ïóòåøåñòâèå èëè ïðîæèâàíèå â ýíäåìè÷íûõ ðåãèîíàõ, ìåäèöèíñêèé ïåðñîíàë, èíôèöèðîâàííûå äîìî÷àäöû, â/â íàðêîìàíèÿ, ãîìîñåêñóàëèçì).
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