Abstract
Euphorbia hirta is a species belonging Euphorbiaceae has been long used by humans as traditional medicine. The plants used as traditional medicine is related to secondary metabolites and its bioactivity. This study aims to explain the utilization and bioactivity of E. hirta. The methods to writing articles is based on a review of articles or research results published online, especially on google scholar, using the keywords Euphorbia hirta, uses of E. hirta and bioactivity of E. hirta then synthesized so that explain the benefits and its bioactivity. Euphorbia hirta is a weed, so that is easily found in the environment which is characterized by the presence of white sap and has cyathia inflorescence. In the traditional medicine E. hirta is used to treat ulcers, dysentery, gastrointestinal infections, skin infections, diabetes mellitus and respiratory disorders are diseases caused by microbial infections. Bioactivity of E. hirta is antimicrobial, antioxidant, anti-diabetes mellitus, anti-stress, anti-cancer and anti-kidney stones. The E. hirta extract contains dedquercetrin, dimethoxyquercetrin, hirta coumaroflavonoside, and hirta flavonoside-B which bioctivity to inhibit α-glucosidase activity comparable to acarbose so that it is potential to be developed as anti-diabetes mellitus.
Highlights
Euphorbia hirta, by the Indonesia local people I known as patikan kebo, is a medicinal plant that has been long used as traditional medicine
E. hirta leaves are used to treatment of ulcers, overcoming dysentery, digestive tract infections, and skin infections [3,4] which are mostly caused by microbial infections
This study aims to reveal the relationship between the use of E. hirta as a traditional medicine and its bioactivity so that its development prospects can be improved
Summary
By the Indonesia local people I known as patikan kebo, is a medicinal plant that has been long used as traditional medicine. This plant is easy to find in the surrounding environment such as yards, roadsides, gardens, rice fields and other land. E. hirta leaves are used to treatment of ulcers, overcoming dysentery, digestive tract infections, and skin infections [3,4] which are mostly caused by microbial infections. Rahyana et al [5] reported that E. hirta is used for the treatment of diabetes, respiratory disorders and gastro-intestinal disorders. Various researchers have successfully reported the bioactivity of E. hirta as antimicrobial, antioxidant, anti-diabetic, and antistress
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