Uticaj stalnog magnetnog polja na sadržaj minerala kostiju starih pacova

Abstract

Introduction: Aging is defined as a consequence of progressive accumulation of metabolic waste, which results in development of various disorders in the structure and function of cells over a number of years. It is followed by loss of bone tissue, where bones become less firm. The cycle of bone remodeling with age becomes longer, and the degree of bone mineralization decreases. Static magnetic fields (SMF) are stable magnetic fields that can be natural or artificial. Their moderate intensity (1mT-1T) affects physiological processes, cells, genetic material, behavior and development. So far, numerous studies have shown different effects of static magnetic fields on cell cultures, experimental animals, and the human population. Aim: Aim of this study was to determine the effect of static magnetic field (SMF) on bone mineral content (BMC) values in aging rats. Material and methods: Male Wistar rats, 3 years old, were used in the experiment. A total of 18 animals were divided into two groups: exposed (experimental group) and unexposed (control group). Nine animals from the experimental group were exposed to 30mT intensity static magnetic field for 10 weeks, while nine control rats were not exposed to the static magnetic field. Bone mineral content was measured by DXA (Dual-Energy X-Ray Absorptiometry. Results: Based on the experiment, it was found that after the exposure to the static magnetic field, in the experimental group, there is a statistically significant increase in the value of BMC in the trunk region and ribs region. In all other regions of interest: head, legs, pelvic bone, spine, total BMC - there were no statistically significant changes in BMC values. Conclusion: In the conducted experiment, a higher increase in the value of BMC was found in animals exposed to the SMF, compared to animals that were not exposed to the static magnetic field.