Abstract
The object of the study: Uterine fibroids (UF) in women of early reproductive age.
 The problem to be solved: Improving the effectiveness of postoperative rehabilitation in women of early reproductive age with uterine fibroids based on the study of its morphological features and improvement of rehabilitation measures.
 The main scientific results: It was found that in women of early reproductive age with UF the most common complaints are posthemorrhagic anemia (61.0 %, or 61 women). Regarding the menstrual cycle, the most common dysmenorrhea – 26.0 % (in 26 women). The importance of heredity in the development of such pathology in young women (32.0 %, or 32 women) was confirmed. The most common localization of fibroids is interstitial – 79.0 % (in 79 women).
 Morphological study found that women of early reproductive age most often have a simple UF, namely 96 % (96 women). Uterine leiomyoma was present in 56 % (56 women).
 A study of the hormonal status of women of early reproductive age found that the mean values of hormones such as follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol, progesterone, prolactin and testosterone were higher before surgery than after. When comparing rehabilitation methods (combined oral contraceptives (COCs) or gonadotropin-releasing hormone agonists (GnRH agonists), it was found that postoperative rehabilitation by using COCs for 6-12 months provides significantly better indicators of recovery of hormonal status, indicating the effectiveness of rehabilitation method.
 Scope of practical application of research results: Practical medicine specializing in the diagnosis, treatment and prevention of recurrence of uterine fibroids.
 Innovative technological product: Improved algorithm of postoperative rehabilitation measures by applying COC for 6-12 months after myomectomy, which provides significantly better results in restoring hormonal status during rehabilitation.
 Scope of application of innovative technological product: clinical medical practice related to the diagnosis, treatment and prevention of recurrence of uterine fibroids.
Highlights
IntroductionThe object of the research The object of the study is uterine fibroids in women of early reproductive age
After analysis, it was found that the average duration of the disease in patients from the main group was 3.3±0.3 years, and the most frequent complaints according collected history were posthemorrhagic anemia (61.0 %, i.e. in 61 women), rapid growth of UF (51.0 %, i.e. in 51 women), pain syndrome (46.0 %, i.e. in 46 women), menstrual dysfunction (43.0 %, i.e. in 43 women), infertility (18.0 %, i.e. in 18 women) and habitual miscarriage (10.0 %, i.e. in 10 women) [9]
The results showed that some of the studied women of early reproductive age were burdened with heredity in the development of UF (32.0 %, or 32 women), in particular in one in five – 19.0 % (19 women) – the first degree of kinship
Summary
The object of the research The object of the study is uterine fibroids in women of early reproductive age. Problem description Uterine fibroids are among the most common benign tumors of the pelvic organs, which occurs in women of all ethnic groups. In women under the age of 35, the frequency of UF is almost 60 %, in women under the age of 50–80 % and its prevalence increases every year, especially in women of early reproductive age [1, 2]. ScienceRise ISSN 2313-8416 No 1 (72), 2021. Women with UF may have no complaints and find it by accident. The main complications that accompany UF are irregular, prolonged bleeding, anemia, chronic pelvic pain, reproductive dysfunction, in particular, difficulty conceiving, miscarriage and infertility [3, 4]
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