Uterine Anomalies and Hypertensive Disorders of Pregnancy: A Retrospective Study [1B

Abstract

INTRODUCTION: Pregnancies associated with uterine anomalies have higher rates of recurrent pregnancy loss, preterm delivery and malpresentation necessitating cesarean delivery. Smaller studies have suggested the link between hypertensive disorders and uterine anomalies as well but thus far, there still remains little data regarding the subject. The purpose of this study was to compare rates of hypertensive disorders in pregnant women with a known uterine anomaly and compare it to the rate in the normal pregnant population. METHODS: Demographic and clinical characteristics of patients who were gravid for more than 20 weeks, had an uterine anomaly, and were seen at OhioHealth facilities from January 1, 2010 to October 7, 2015 were examined. The rate of hypertensive disorders among women with uterine anomalies was calculated and compared to the rate of hypertensive disorders among women without uterine anomalies (i.e., the normal pregnant population). RESULTS: From January 1, 2010 to October 7, 2015, there were 80 women seen at OhioHealth facilities who were gravid for more than 20 weeks and had a uterine anomaly. A greater proportion of women with a uterine anomaly had a hypertensive disorder (15.0%) than women without a uterine anomaly (5.0%) (p=0.001). CONCLUSION: A greater proportion of women with a uterine anomaly had a hypertensive disorder (15.0%) than women without a uterine anomaly (5.0%) (p=0.001). With increasing use of assisted reproductive technology, the OB/GYN community will begin seeing a greater number of these pregnancies. Understanding the specific pregnancy outcomes that are associated with these high risk pregnancies will be crucial for appropriate management.