Abstract
PurposeThe aims of this study were to determine whether post transplant renal scan performed at around 1 week can predict graft failure, and to identify the best predictive factors among easy-to-measure variables.Materials and methodsWe retrospectively evaluated patients who underwent Tc-99m DTPA renal scan at approximately 1 week after renal transplantation. They were separated into two categories at 3 months after the operation; graft failure and non-failure. Graft failure was confirmed by biopsy (rejection). Non-failure was confirmed either by biopsy or clinical follow-up with serum creatine (Cr). Scan parameters including glomerular filtration rate (GFR), Hilson perfusion index, peaks of the iliac and graft perfusion curves were analyzed. Clinical variables including age, sex, height, weight, systolic blood pressure, serum Cr, type of donated kidney, side of transplant, and immunosuppressant were also analyzed.ResultsAmong total 45 patients, graft failure was present in 11 cases. The serum Cr level was significantly higher in the failure group. Among scan variables, only the GFR was significantly different between groups. GFR of <44.48 mL/min was predictive of graft failure (sen 88.9%). Serum Cr level >2.13 mg/dL was also predictive (sen 72.7%).ConclusionGFR on renal scan at approximately 1 week after kidney transplant can predict graft failure.
Highlights
glomerular filtration rate (GFR) of
Graft rejection after kidney transplant is a major problem, and a reliable predictor of graft function is necessary for optimal management of renal transplant patients [1]
Previous studies have revealed good results with scintigraphy in transplanted kidneys. Most of these studies have relied on early scanning, which was performed within 4 days, and even at 1 day, post transplant [3,4,5,6,7,8,9,10,11], and a comparison of post transplant scans at 3 days and 7 days postoperatively in the same patient seemed to show that only the post transplant day-3 scan could predict the graft outcome [10]
Summary
The aims of this study were to determine whether post transplant renal scan performed at around 1 week can predict graft failure, and to identify the best predictive factors among easy-to-measure variables. The aims of this study were to find out whether a renal scan performed at approximately 1 week post transplant can be used to predict graft failure and to identify the best predictive factors among easy-to-measure variables
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
