Abstract
The aims of our study were analysis of the bioactive chemical products and determination of antibacterial activity. Twenty eight bioactive compounds were identified in the methanolic extract of Penicillium italicum. The identification of bioactive chemical compounds is based on the peak area, retention time molecular weight and molecular formula. The results of anti-fungal and anti-bacterial activity produced by Penicillium italicum showed that the volatile compounds were highly effective to suppress the growth of Aspergillus terreus 6.302±0.20 mm and Proteus mirabilis 6.08±0.21 mm. In agar well diffusion method the selected medicinal plants were effective against Penicillium italicum. Melissa officinalis was very highly antifungal activity 6.70±0.25 mm.
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