Using Binary-coded Bat Algorithm to Solve Hydrophobic-Polar Model Structure

Abstract

Hydrophobic-Polar model structure prediction problem is one important issue in molecular biology. This problem is to determining the native two-dimensional structure of a protein when giving the sequence of amino acid residues. Recently, a novel swarm intelligent algorithm, bat algorithm is proposed. In this paper, a new binary-coded bat algorithm is designed and applied to solve it. To show the validity of proposed algorithm, four protein sequences are employed to compare, and simulation results show it is effective.