Abstract
We have developed a polymerase chain reaction (PCR) system for typing group specific component (Gc). Our Gc DNA typing system has several advantages: 1. The 2, 1F and 1S Gc alleles can be typed unambiguously. 2. An individual’s Gc type can be obtained from any biological sample from which DNA can be isolated and amplified (e.g. blood, hair, semen, saliva, bone). 3. The Gc typing can be combined with other genetic marker systems typed by DNA analysis (e.g. HLA DQα) to give a very high power of discrimination.
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