Abstract
The selected bile acids such as: cholic acid (C), glycocholic acid (GC), glycolithocholic acid (GLC), deoxycholic acid (DC), chenodeoxycholic acid (CDC), glycodeoxycholic acid (GDC), lithocholic acid (LC), were separated by using normal phase thin-layer chromatography (NP-TLC) on glass plates precoated with silica gel 60 with concentrating zone (E. Merck, #1.11845) and n-hexane-ethyl acetate–methanol-acetic acid in volume composition 20:20:5:2 as the mobile phase. The selected topological indexes based on connectivity (Mν, 0χν, 1χν, 2χν, and ), on distance matrix (W, A, 0B, 1B, and C), and selected electrotopological states (SdO(acid), SsOH(acid), SsOH(aliph), SdO(amide), and SsNH) were calculated for investigated bile acids. The most accurate prediction of the RM values of the investigated bile acids was achieved by using a monoparametric equation employing the topological index Mν.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
