Abstract
Nutraceuticals are foods or part of a food that provide health benefits, including the prevention and / or treatment of diseases. In this sense, curcumin, the main active compound of turmeric, popularly known as saffron, deserves considerable attention as a nutraceutical because, despite high chemical instability, it can prevent and treat complex multigenic diseases, mainly due to its antioxidant action. Therefore, nanotechnology comprises an important tool to improve compounds with proven therapeutic activity, but with a reduced pharmacokinetic profile, such as curcumin. This literature review describes the results of studies using nanostructured systems containing curcumin as nutraceuticals. The systematic review of the literature was carried out by searching for original articles that addressed the topic of interest published in the last 10 years. The results showed variety regarding the type of polymer and the method of obtainment used in the preparation of nanostructured systems described in the literature. However, in general, nanoencapsulated curcumin showed similarities in its physico-chemical characteristics and better biological performance when compared to free curcumin, overcoming the limitations of its use. Therefore, curcumin is a good example of a naturally occurring substance which therapeutic properties can be enhanced through the use of nanotechnology.
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