Abstract
There are two main approaches to visual function prosthesis in blind patients with the use of «brain-computer» interfaces – on the basis of either retinal or cortical stimulation by implanted electrodes. The most complex in visual prosthesis is creation of the specific part of the interface that directly contacts with the tissues. In the paper discussed are questions of biocompatibility of microelectrode arrays and behavioral effects on animals (cats) for evaluating functionality of the bioprosthetic device and its ability to induce phosphenes (visual sensations without light). Presented are new experimental methods and obtained results that allowed to determine phospheneinducing parameters of brain cortex electric stimulation in cats. Special attention is focused on description of the microelectrode array properties necessary for safe application in humans during the long time span, which is essential in cortical visual prosthesis.
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