Abstract
Background: The determination of clonal T-cell populations in diagnostic flow cytometry has been more complex than that of B cells, hindering widespread availability. T-cells with αẞ T-cell receptor express a TCR ẞ-chain constant region encoded by either TRBC1, named JOVI.1, or TRBC2. We investigated the use of anti-JOVI.1 monoclonal antibodies in a large tertiary diagnostic flow cytometry laboratory.
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