Abstract
Colic mucosa was used as a graft for urethral construction in 9 Sprague-Dawley rats. A urethrectomy was performed in each rat and then a urethroplasty built with the colic mucosa taken from a segmental colectomy. After 6 weeks to 3 months, all of these rats developed a typical urothelium. The digestive mucosa has been transformed into urothelium or acts as a stent to guide regrowth from each end. These results are encouraging, but the use of the appendix mucosa for hypospadias repair and for urethroplasty deserves further study.
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