Usage of Flaxseed Lignan in Menaposal Complaınts in Perımenaposal Women Patıents

Hayriye Alp

doi:10.31579/2578-8965/092

Abstract

Lignans are phenylpropanoid dimers widely distributed in the plant kingdom. Flaxseed (Linum usitatissimum) is one of the richest sourcase of dietary lignans. Plant lignans comprise one of the two main groups of phytoestrogens the other group beigng the isoflavonoids. The major flax lignan is secoisolariciresinol diglucoside (SDG).Flaxseed is the richest food sourcase of SDG.Flaxseed also contains much smaller amounts of matairesinol, lariciresinol, and pineresinol. The plant lignans are converted by the intestinal microflora in the proximal or upper part of the large intestine to enterodiol (END) and enterolactone (ENL). Between 2017 and 2019, 26 female patients who applied for getat polk, obesity and perimenopausal complaints were included in the study. Demographic data of the patients were recorded. Age, weight, height, BMI and bloodT3,4, TSH, B12, Na, K levels were measured. Statistically average measurements were taken. Flaxseed was recommended for patients whose cholesterol levels were above the reference value. SDG has antioksidant activity.It also may have hypoglycemic, hypocholesterolemic, estrogenic,anti-estrogenic, anticancer, antiproliferative and renoprotective properties.

Highlights

Lignans are phenylpropanoid dimers widely distributed in the plant kingdom
The plant lignans are converted by the intestinal microflora in the proximal or upper part of the large intestine to enterodiol(END) and enterolactone (ENL).END and ENL are not themselves plant lignans and are called mammalian lignans or enterolinans
The spruce lignan 7hydroxymatairesinol processes this type of chemical structure(see spruce lignans).the other major chemical type is the tetrahydrofuran type that can be found in the sesame seed lignans sesamin and sesaminol

Summary

Introduction

Lignans are phenylpropanoid dimers widely distributed in the plant kingdom. Flaxseed (Linum usitatissimum) is one of the richest sourcase of dietary lignans. The major flax lignan is secoisolariciresinol diglucoside(SDG).Flaxseed is the richest food sourcase of SDG.Flaxseed contains much smaller amounts of matairesinol, lariciresinol, and pineresinol. It is thought that many of the possible biological actions of SDG are due to its convertion to END and ENL.SDG is dibenzylbutyrolactone.

Results

Conclusion