Abstract
Abstract—Physical urticarias represent a group of diseases of indeterminate cause, whose treatment is at times difficult. Cold urticaria is brought on by the exposure of the skin to low temperatures, and patients who suffer from it must be studied to rule out cryopathy, especially the presence of cryoglobulins in the blood. Treatment of cold urticaria may be disappointing, and it is usually based on a combination of H1-antihistamines. According to published studies, leukotrienes are important mediators in cold urticaria, and its successful treatment using leukotriene antagonist drugs has been reported, alone or combined with antihistamines.We describe a case of cold urticaria that was controlled through the combined administration of cetirizine and montelukast.
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