Abstract
We investigated the relationship between histological composition of the prostate and urodynamic outcome after transurethral resection of the prostate (TURP) in 27 patients with symptomatic benign prostatic hyperplasia (BPH). The histological analysis was performed using computer-assisted quantitative morphometry. Before and after TURP, group-specific urethral resistance factor (URA) was estimated by pressure-flow study. A significant correlation was found (p = 0.01) between the area density of prostate smooth muscle and the improvement in URA. However, no other histological components correlated with the improvement in URA. These facts suggest that the percent area density of prostate smooth muscle in prostatic adenoma appears to be a useful predictive factor for treatment of BPH.
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