Urinary Pb levels in schoolchildren from the largest coal mining area in Brazil and its associated factors: a cross-sectional study.

Abstract

Candiota region has the largest coal reserve in Brazil, and previous studies have shown moderate-high levels of metals in the environment, including Pb. On the other hand, there are no studies investigating the factors associated with high levels of urinary Pb in children in the region. To investigate this issue, a cross-sectional study was conducted with 92 schoolchildren from 7 cities comprising this coal-mining region. Socioeconomic and demographic information and parental life habits and children's health information were collected using a semi-structured questionnaire. Diurnal urine samples were collected to quantify Pb levels (µg/g creatinine). Bi- and multivariate Poisson regression with a robust estimator was used to assess factors associated with high levels of Pb. Urinary Pb levels in children in the region vary from not detected to 21.6µg/g of creatinine. The spatial distribution of urinary Pb levels in children indicated an influence of proximity to mining areas, and this factor was confirmed by Poisson regression analysis (bivariate). Other factors associated with high levels of urinary Pb were non-white mothers, paternal occupational exposure, and low BMI. The findings of this study reveal that the Candiota region is a hotspot for high levels of urinary Pb in children (geometric mean: 3.82µg/g creatinine) and that, in addition to the proximity to mining areas, factors socioeconomic and health conditions may be associated with these high levels.