Abstract
The urinary excretion of LH, low polar oestrogens (oestrone + oestradiol-17β), dehydroepiandrosterone, androsteone, aetiocholanolone, pregnanediol and total 17-keto-and 17-ketogenic steroids has been determined in 30 men aged 60–84 years with benign prostatic hyperplasia and in 39 healthy men aged 60–79 years. The results show a significantly elevated oestrogen excretion in benign prostatic hyperplasia as compared with the control group. No other significant differences were found in the urinary hormone excretion. It is speculated that the increased oestrogen levels might stimulate the prostate growth mainly by facilitating the transport of peripheral testosterone into prostate cell.
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