Abstract
AbstractThe urethral pressure and pressure variations were studied in ten genuine stress incontinent women and twenty‐six women with unstable detrusor based on 1 hour recordings. In the stress incontinent women the mean maximum urethral pressure (mMUP) calculated from 1 hour continuous urethral pressure recordings was 49 cm H2O and the mean maximum urethral closure pressure (mMUCP) was 38 cm H2O. When analysed in relation to previous data from healthy women the mMUP and the mMUCP were significantly reduced. The urethral pressure variation (UPV) is a normal physiological activity of the urethra, also occurring in stress incontinent and unstable detrusor patients. The UPV amplitude of the stress incontinent women was reduced, indicating that the UPVs are related to the baseline pressure in urethra but still part of the complex pathophysiological changes occurring in urethra during stress incontinence. In the unstable detrusor group the parameters were within the range of the normal material except for the abrupt urethral pressure drop followed by detrusor contraction. However, these events were clearly different from the rhythmic urethral pressure variations which seem to discern from the pathogenesis of the unstable detrusor.
Published Version
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