Uptake and Release of Species from Carbohydrate Containing Organogels and Hydrogels.

Abhishek Pan,Ujjal Haldar,Priyadarsi De,Rita D Mahapatra,John G Hardy,Saswati G Roy,Wan Li Low,Garry R Harper

doi:10.3390/gels5040043

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Hydrogels are used for a variety of technical and medical applications capitalizing on their three-dimensional (3D) cross-linked polymeric structures and ability to act as a reservoir for encapsulated species (potentially encapsulating or releasing them in response to environmental stimuli). In this study, carbohydrate-based organogels were synthesized by reversible addition-fragmentation chain transfer (RAFT) polymerization of a β-D-glucose pentaacetate containing methacrylate monomer (Ac-glu-HEMA) in the presence of a di-vinyl cross-linker; these organogels could be converted to hydrogels by treatment with sodium methoxide (NaOMe). These materials were studied using solid state 13C cross-polarization/magic-angle spinning (CP/MAS) NMR, Fourier transform infrared (FTIR) spectroscopy, and field emission scanning electron microscopy (FE-SEM). The swelling of the gels in both organic solvents and water were studied, as was their ability to absorb model bioactive molecules (the cationic dyes methylene blue (MB) and rhodamine B (RhB)) and absorb/release silver nitrate, demonstrating such gels have potential for environmental and biomedical applications.

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The fundamental science and engineering that underpins the development of gels with customizable properties and structures enables the production of materials with a variety of task-specific applications, potentially delivering beneficial economic, environmental, health and societal impacts [1,2,3,4,5,6,7].Materials science underpins products worth billions of dollars and directly/indirectly supports millions of jobs worldwide
13]. aGels are the of areviews multitude of review articles, and a comprehensive review of the towards selection of subject insightful chemistry, engineering and physics of such materials is outside the scope of this communication, and for Polysaccharides of natural and synthetic origins are a common component of gels used the interested reader is directed towards a selection of insightful reviews biomedical applications because they tend to be cheap and their properties are tuned; natural and synthetic origins are a common component of gels used for they tend Polysaccharides to be relativelyof non-immunogenic which is important for biomedical applications [19,20,21,22,23]. Biomedical applications because they tend to be cheap and their properties are tuned; we report the preparation of carbohydrate-based gels via the reversible-addition they tend to be relatively non-immunogenic which is important for biomedical fragmentation chain transfer (RAFT) polymerization [24,25] of β-D-glucose pentaacetate containing applications [19,20,21,22,23]
We previously reported that 4-cyano-4-(dodecylsulfanylthiocarbonyl)sulfanylpentanoic acid (CDP) actsWe as have an efficient chain transfer agent (CTA) for the reversible addition-fragmentation chain transfer (RAFT) polymerization of methacrylated previously reported that

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The fundamental science and engineering that underpins the development of gels with customizable properties and structures enables the production of materials with a variety of task-specific applications, potentially delivering beneficial economic, environmental, health and societal impacts [1,2,3,4,5,6,7].Materials science underpins products worth billions of dollars and directly/indirectly supports millions of jobs worldwide. The fundamental science and engineering that underpins the development of gels with customizable properties and structures enables the production of materials with a variety of task-specific applications, potentially delivering beneficial economic, environmental, health and societal impacts [1,2,3,4,5,6,7]. Gels are a class of materials with properties suitable for a variety of technical and medical applications [1,2,3,4,5,6,7] that capitalize on their three-dimensional (3D) cross-linked polymeric structures and ability to act as a reservoir for encapsulated species. Gels can encapsulate and/or release species, potentially in response to. Gels are the subject of a multitude of review articles, and a comprehensive review of the chemistry, engineering and physics

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