Abstract
We investigated the effects of β-amyloid peptide precursor (APP) overexpression upon the levels of other mRNAs. Using quantitative slot-blot hybridization and immunoblot analysis we observed that enhanced levels of APP elevated the levels of β-actin and β-actin mRNA. Our results also suggest that the cytoplasmic domain of APP is crucial for the elevation in β-actin gene expression.
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Schedule a callMore From: Biochemical and Biophysical Research Communications
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