Upper Arm Deep Vein Thrombosis in a Patient with Active Lupus.

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To highlight the possibility of idiopathic upper extremity deep vein thrombosis (UEDVT) in spontaneous unilateral arm swelling.Idiopathic UEDVT might indicate a serious underlying autoimmune condition as SLE in this case (in the absence of antiphospholipid syndrome), that requires intensive thorough investigation by a multidisciplinary team.Initial treatment of both UEDVT and lupus nephritis with standard dose anticoagulants and steroids might be the proper initial management, whereas kidney biopsy might not be necessary as the risk of bleeding is high while on anticoagulants.