Upholding trust in therapeutic trials and evidence-based medicine: need for full disclosure of data, crowdsourcing data analysis and independent review?

Pierre Vladimir Ennezat,Thierry H Le Jemtel,Raphaëlle Ashley Guerbaai

doi:10.1136/bmjebm-2019-111242

Upholding trust in therapeutic trials and evidence-based medicine: need for full disclosure of data, crowdsourcing data analysis and independent review?

Pierre Vladimir Ennezat, Thierry H Le Jemtel + Show 1 more

https://doi.org/10.1136/bmjebm-2019-111242

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Journal: BMJ Evidence-Based Medicine

Publication Date: Jul 23, 2021

Affiliation: Centre Hospitalier Universitaire de Grenoble, Tulane University

#Low-density Lipoprotein Cholesterol #European Society Of Cardiology Guidelines #Family History Of Hypercholesterolaemia #High Cardiovascular Risk Factors #Distrust In Vaccination #Crowdsourcing Data Analysis #Postponement Of Death #Targeting Low-density Lipoprotein Cholesterol #Secondary Prevention Trials #Absolute Risk Reduction

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An active 74-year-old woman with hypertension and a family history of hypercholesterolaemia was referred for evaluation of chest pain and underwent coronary angiography. Low-density lipoprotein (LDL) cholesterol was 270 mg/dL....

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Upholding trust in therapeutic trials and evidence-based medicine: need for full disclosure of data, crowdsourcing data analysis and independent review?