Abstract
Pertussis or whooping cough is an acute infectious disease of the respiratory system,which is mainly caused by Bordetella pertussis and Bordetella parapertussis. It can occur at any age,but is most serious in young infants. Despite widespread use of vaccination, pertussis has not been eliminated. On the contrary, increased incidence rates have been reported worldwide during the last two decades,also called reemergence of pertussis. So it is necessary to evaluate current state on pertussis research,in order to better provide basis for monitoring and control pertussis. This paper reviews the pertussis epidemiological changes and the related cause analysis and immunization strategy. Key words: Pertussis; Bordetella pertussis; Epidemiology
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