Abstract

Pertussis is an severe infectious respiratory disease that continues to be a serious public health problem, which is caused by Bordetella Pertussis.Because it's highly infectivity, it is still an important etiological factor associated with persistent cough in adults and adolescents.With the introduction of mass vaccination in 1974, there has been a dramatic decrease in the morbidity and mortality.However, in recent years, increasing numbers of pertussis are reported in adolescents and adults in many countries where with high vaccination coverage.The thesis summarize and discuss the progress of pertussis epidemiology and clinical characteristics. Key words: Bordetella pertussis; Clinical characteristics; Epidemiology

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