Abstract
Using Monte Carlo simulations, we study the hysteresis in unzipping of a double-stranded block copolymer DNA with -A_{n}B_{n}- repeat units. Here A and B represent two different types of base pairs having two and three bonds, respectively, and 2n represents the number of such base pairs in a unit. The end of the DNA are subjected to a time-dependent periodic force with frequency (ω) and amplitude (g_{0}) keeping the other end fixed. We find that the equilibrium force-temperature phase diagram for the static force is independent of the DNA sequence. For a periodic force case, the results are found to be dependent on the block copolymer DNA sequence and on the base pair type on which the periodic force is acting. We observe hysteresis loops of various shapes and sizes and obtain the scaling of loop area both at low- and high-frequency regimes.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
